A research printed within the Journal of Basic Virology confirmed that curcumin can forestall Transmissible gastroenteritis virus (TGEV) — an alpha-group coronavirus that infects pigs — from infecting cells. At increased doses, the compound was additionally discovered to kill virus particles.
An infection with TGEV causes a illness referred to as transmissible gastroenteritis in piglets, which is characterised by diarrhea, extreme dehydration and dying. TGEV is extremely infectious and is invariably deadly in piglets youthful than two weeks, thus posing a significant risk to the worldwide swine business. There are at present no permitted therapies for alpha-coronaviruses and though there’s a vaccine for TGEV, it isn’t efficient in stopping the unfold of the virus.
To find out the potential antiviral properties of curcumin, the analysis workforce handled experimental cells with numerous concentrations of the compound, earlier than making an attempt to contaminate them with TGEV. They discovered that increased concentrations of curcumin decreased the variety of virus particles within the cell tradition.